Supplementary Information for Impact of regulatory variation across human iPSCs and differenti- ated cells
نویسندگان
چکیده
1Department of Human Genetics, University of Chicago, Chicago, IL, USA. 2Department of Genetics, Stanford University, Stanford, CA, USA. 3Department of Medicine, University of Chicago, Chicago, IL, USA. 4Department of Biomedical Informatics, Stanford University, Stanford, CA, USA. 5Department of Biology, Stanford University, Stanford, CA, USA. 6Howard Hughes Medical Institute, Stanford, University, Stanford, CA, USA. ‡Present address. Translational Genomics Research Institute, Phoenix, AZ, USA (N.E.B.); Centre for Systems Genomics,
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Impact of regulatory variation across human iPSCs and differentiated cells.
Induced pluripotent stem cells (iPSCs) are an essential tool for studying cellular differentiation and cell types that are otherwise difficult to access. We investigated the use of iPSCs and iPSC-derived cells to study the impact of genetic variation on gene regulation across different cell types and as models for studies of complex disease. To do so, we established a panel of iPSCs from 58 wel...
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تاریخ انتشار 2017